GEL FORMULATION OF GUAVA LEAF (PSIDIUM GUAJAVA LINN) ETHANOL EXTRACT WITH HPMC (HIDROKSIPROPIL METIL SELULOSA) AS GEL BASE

Rahmawati, Suci and Syalfinaf, Manaf and Chausi, Artini (2018) GEL FORMULATION OF GUAVA LEAF (PSIDIUM GUAJAVA LINN) ETHANOL EXTRACT WITH HPMC (HIDROKSIPROPIL METIL SELULOSA) AS GEL BASE. In: THE 1th INTERNATIONAL CONFERENCE ON INTERPROFESSIONAL HEALTH COLLABORATION, October 30-31th 2018, GRAGE HOTEL BENGKULU, INDONESIA.

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Abstract

In this study gel was formulated from 5% guava leaf (Psidium guajava Linn) ethanol extract with variation of HPMC concentrations as gel base, they were 1%, 1.5% and 2%. This study was aimed to formulated gel from 5% guava leaf extract. Guava leaf extract was obtained by using maceration method. Guava gel was formulated in 3 formulas with HPMC, they were FI 1% of HPMC, FII 1.5% of HPMC and FIII 2% of HPMC. Gel of guava leaf ethanol extract was evaluated in various parameters like organoleptic, homogeneity, pH, spreadability, adhesion, stability study and irritation test. The results can be concluded that FIII has best characteristic from other. FIII was transparent gel, homogeneous, has a good spreadability (in a range 5.15.8 cm), adhesion (5.35 minutes) and stability. FIII does not irritating skin when applied (pH 6).

Item Type: Conference or Workshop Item (Paper)
Subjects: Q Science > Q Science (General)
Divisions: Faculty Of Medicine > Department Of Medical Science
Depositing User: Septi Septi
Date Deposited: 15 Jul 2019 05:09
Last Modified: 15 Jul 2019 05:09
URI: http://repository.unib.ac.id/id/eprint/18822

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